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recombinant human growth factor β1  (MedChemExpress)


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    Structured Review

    MedChemExpress recombinant human growth factor β1
    Recombinant Human Growth Factor β1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 31 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/growth+factor+%CE%B21/TGF+beta+1%2FTGFB1%2C+Human/pm42574784-82-13-19
    Average 98 stars, based on 31 article reviews
    recombinant human growth factor β1 - by Bioz Stars, 2026-09
    98/100 stars

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    Related Articles

    Activation Assay:

    Article Title: Inhibition of SGK3 regulates hyperplastic scar development in rats through the MAPK/ERK signaling pathway.
    Article Snippet: Hypertrophic scars (HS) frequently result from severe burns, surgical procedures and other causes of deep skin damage.. The impact of serum/glucocorticoid regulated kinase family member 3 (SGK3) on the formation of HS remains unclear.. HS model rats were constructed by the scalding method.

    In Vitro:

    Article Title: Maternal immune activation induces epilepsy- patent foramen ovale comorbidity in offspring.
    Article Snippet: The HUVECs were incubated with 2 x 108 Tu/ml LV-YAP-shRNA or negative control in HiTransG medium for 48 h. The transfection efficiency was monitored using fluorescent inverted microscope (DMi8, Leica, Germany). .. We established the EndMT model in vitro by incubating HUVECs for 48 h in starvation medium containing 100 ng/ml transforming growth factor-β1 (TGF-β1, MedChemExpress, China). ..

    Recombinant:

    Article Title: Linderalactone attenuates pulmonary fibrosis by suppressing HIF-1α-associated ferroptotic stress.
    Article Snippet: Ethnopharmacological relevance: Linderalactone is a sesquiterpene lactone isolated from Linderae Radix, a traditional Chinese medicinal herb used for pain and inflammatory disorders.. Given the roles of hypoxia-related signaling, oxidative stress, and iron-dependent lipid peroxidation in fibrotic lung remodeling, linderalactone was evaluated as a natural product-derived anti-fibrotic lead.. Aim of the study: To evaluate the anti-pulmonary fibrosis activity of linderalactone and determine whether modulation of HIF-1α-dependent ferroptotic stress contributes to its underlying mechanism.

    Article Title: Targeting the SMAD3/CISD2 axis suppresses bladder cancer progression by promoting ferroptosis in mesenchymal-like bladder cancer cells.
    Article Snippet: .. Chemical reagents used in this study included: recombinant human transforming growth factor β1 (TGF-β1, HYP78168), ferroptosis inducers Erastin (HY-15763) and RSL3 (HY-100218A), ferroptosis inhibitor Ferrostatin-1 (Fer1, HY-100579), and iron chelator Deferoxamine mesylate (DFO, HY-B0988), all purchased from MedChemExpress (MCE) with purity ≥ 98%. ..

    Article Title: Targeting the SMAD3/CISD2 axis suppresses bladder cancer progression by promoting ferroptosis in mesenchymal-like bladder cancer cells
    Article Snippet: .. Chemical reagents used in this study included: recombinant human transforming growth factor β1 (TGF-β1, HY- P78168 ), ferroptosis inducers Erastin (HY-15763) and RSL3 (HY-100218A), ferroptosis inhibitor Ferrostatin-1 (Fer-1, HY-100579), and iron chelator Deferoxamine mesylate (DFO, HY-B0988), all purchased from MedChemExpress (MCE) with purity ≥98%. ..

    Control:

    Article Title: Baicalin inhibits A549 cells proliferation and EMT through targeting the EGFR pathway.
    Article Snippet: Background: The high global incidence and mortality rates of lung cancer present a persistent worldwide health challenge.. In this context, the epidermal growth factor receptor (EGFR) oncogene and the epithelialmesenchymal transition (EMT) process are heavily implicated in tumor progression and invasiveness.. Although the plant-Scutellaria baicalensis-derived flavonoid glycoside Baicalin potently suppresses lung cancer cell growth, its specific roles in modulating the EGFR signaling axis and EMT remain to be elucidated.

    Marker:

    Article Title: Prophylactic systemic low-dose pirfenidone attenuates intrauterine adhesion by inhibiting the TGF-β1/Smad3 pathway.
    Article Snippet: Background: Intrauterine adhesion (IUA) is a severe fibrotic disorder lacking effective non-surgical treatments.. This study explored pirfenidone (PFD), an antifibrotic drug approved for treating lung fibrosis, as a potential

    Expressing:

    Article Title: Prophylactic systemic low-dose pirfenidone attenuates intrauterine adhesion by inhibiting the TGF-β1/Smad3 pathway.
    Article Snippet: Background: Intrauterine adhesion (IUA) is a severe fibrotic disorder lacking effective non-surgical treatments.. This study explored pirfenidone (PFD), an antifibrotic drug approved for treating lung fibrosis, as a potential

    Western Blot:

    Article Title: Prophylactic systemic low-dose pirfenidone attenuates intrauterine adhesion by inhibiting the TGF-β1/Smad3 pathway.
    Article Snippet: Background: Intrauterine adhesion (IUA) is a severe fibrotic disorder lacking effective non-surgical treatments.. This study explored pirfenidone (PFD), an antifibrotic drug approved for treating lung fibrosis, as a potential



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    Temporal analysis of the BMSC paracrine profile on different scaffolds. (A) Confocal microscopy images from Live/Dead fluorescence staining of BMSCs encapsulated within the PCL/HAp-GelMA/BMSCs scaffold after 1, 3, 5, and 14 d of 3D culture (live cells, green; dead cells, red). (B) The concentrations of key paracrine factors <t>(TGF-β,</t> <t>PGE2,</t> VEGF, HGF, and BMP-2) from BMSCs cultured in different scaffolds, quantified from culture supernatants at day 3 and day 7. (C) Corresponding relative mRNA expression levels of TGFB1, PTGS2, VEGFA, HGF, and BMP-2 in BMSCs at day 3 and day 7, as determined by qPCR analysis. Data are presented as mean ± SD (n = 3) *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; ns: not significant.
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    Temporal analysis of the BMSC paracrine profile on different scaffolds. (A) Confocal microscopy images from Live/Dead fluorescence staining of BMSCs encapsulated within the PCL/HAp-GelMA/BMSCs scaffold after 1, 3, 5, and 14 d of 3D culture (live cells, green; dead cells, red). (B) The concentrations of key paracrine factors <t>(TGF-β,</t> <t>PGE2,</t> VEGF, HGF, and BMP-2) from BMSCs cultured in different scaffolds, quantified from culture supernatants at day 3 and day 7. (C) Corresponding relative mRNA expression levels of TGFB1, PTGS2, VEGFA, HGF, and BMP-2 in BMSCs at day 3 and day 7, as determined by qPCR analysis. Data are presented as mean ± SD (n = 3) *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; ns: not significant.
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    Affinity Biosciences transforming growth factor β1 tgf β1 antibody
    In vivo therapeutic efficacy. (A) TNF-α, (B) IL-1β, (C) SOD, and (D) MDA levels in renal tissues after different drug treatments. (E) Immunofluorescence detection of CD86 expression in the glomeruli. Scale bars: 100 μm. (F) Immunofluorescence detection of 8-OHdG expression in the kidney. Scale bars: 300 μm. (G) Immunofluorescence detection of PDGF-BB <t>and</t> <t>TGF-β1</t> expression in the glomeruli. Scale bars: 100 μm. (H-K) Fluorescence statistical graph of CD86, 8-OHdG, PDGF-BB, and TGF-β1. ∗ P < 0.05 and ∗∗ P < 0.01.
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    In vivo therapeutic efficacy. (A) TNF-α, (B) IL-1β, (C) SOD, and (D) MDA levels in renal tissues after different drug treatments. (E) Immunofluorescence detection of CD86 expression in the glomeruli. Scale bars: 100 μm. (F) Immunofluorescence detection of 8-OHdG expression in the kidney. Scale bars: 300 μm. (G) Immunofluorescence detection of PDGF-BB <t>and</t> <t>TGF-β1</t> expression in the glomeruli. Scale bars: 100 μm. (H-K) Fluorescence statistical graph of CD86, 8-OHdG, PDGF-BB, and TGF-β1. ∗ P < 0.05 and ∗∗ P < 0.01.
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    Image Search Results


    Temporal analysis of the BMSC paracrine profile on different scaffolds. (A) Confocal microscopy images from Live/Dead fluorescence staining of BMSCs encapsulated within the PCL/HAp-GelMA/BMSCs scaffold after 1, 3, 5, and 14 d of 3D culture (live cells, green; dead cells, red). (B) The concentrations of key paracrine factors (TGF-β, PGE2, VEGF, HGF, and BMP-2) from BMSCs cultured in different scaffolds, quantified from culture supernatants at day 3 and day 7. (C) Corresponding relative mRNA expression levels of TGFB1, PTGS2, VEGFA, HGF, and BMP-2 in BMSCs at day 3 and day 7, as determined by qPCR analysis. Data are presented as mean ± SD (n = 3) *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; ns: not significant.

    Journal: Bioactive Materials

    Article Title: Mesenchymal stromal cells-loaded 3D radially aligned composite scaffold with potentiated paracrine signaling for sequential bone regeneration

    doi: 10.1016/j.bioactmat.2026.02.059

    Figure Lengend Snippet: Temporal analysis of the BMSC paracrine profile on different scaffolds. (A) Confocal microscopy images from Live/Dead fluorescence staining of BMSCs encapsulated within the PCL/HAp-GelMA/BMSCs scaffold after 1, 3, 5, and 14 d of 3D culture (live cells, green; dead cells, red). (B) The concentrations of key paracrine factors (TGF-β, PGE2, VEGF, HGF, and BMP-2) from BMSCs cultured in different scaffolds, quantified from culture supernatants at day 3 and day 7. (C) Corresponding relative mRNA expression levels of TGFB1, PTGS2, VEGFA, HGF, and BMP-2 in BMSCs at day 3 and day 7, as determined by qPCR analysis. Data are presented as mean ± SD (n = 3) *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; ns: not significant.

    Article Snippet: ELISA kits for PGE2 (Cat. No. E-EL-0034), TGF-β (Cat. No. E-EL-0162), VEGF (Cat. No. E-EL-R2603), and HGF (Cat. No. E-EL-R0496) were purchased from Elabscience (Wuhan, China).

    Techniques: Confocal Microscopy, Fluorescence, Staining, Cell Culture, Expressing

    In vivo therapeutic efficacy. (A) TNF-α, (B) IL-1β, (C) SOD, and (D) MDA levels in renal tissues after different drug treatments. (E) Immunofluorescence detection of CD86 expression in the glomeruli. Scale bars: 100 μm. (F) Immunofluorescence detection of 8-OHdG expression in the kidney. Scale bars: 300 μm. (G) Immunofluorescence detection of PDGF-BB and TGF-β1 expression in the glomeruli. Scale bars: 100 μm. (H-K) Fluorescence statistical graph of CD86, 8-OHdG, PDGF-BB, and TGF-β1. ∗ P < 0.05 and ∗∗ P < 0.01.

    Journal: Materials Today Bio

    Article Title: Biomimetic self-assembled nanosoldiers of paotianxiong polysaccharides and α-lipoic acid: Highly specific targeted therapy for mesangial proliferative glomerulonephritis

    doi: 10.1016/j.mtbio.2026.103313

    Figure Lengend Snippet: In vivo therapeutic efficacy. (A) TNF-α, (B) IL-1β, (C) SOD, and (D) MDA levels in renal tissues after different drug treatments. (E) Immunofluorescence detection of CD86 expression in the glomeruli. Scale bars: 100 μm. (F) Immunofluorescence detection of 8-OHdG expression in the kidney. Scale bars: 300 μm. (G) Immunofluorescence detection of PDGF-BB and TGF-β1 expression in the glomeruli. Scale bars: 100 μm. (H-K) Fluorescence statistical graph of CD86, 8-OHdG, PDGF-BB, and TGF-β1. ∗ P < 0.05 and ∗∗ P < 0.01.

    Article Snippet: Transforming growth factor-β1 (TGF-β1) antibody was obtained from Jiangsu Affinity Biosciences Co., Ltd. (Changzhou, China).

    Techniques: In Vivo, Drug discovery, Immunofluorescence, Expressing, Fluorescence